|
KMID : 0604520150410020181
|
|
Journal of the Society of Cosmetic Scientists of Korea
2015 Volume.41 No. 2 p.181 ~ p.187
|
|
|
Antioxidant Activities of Gynura procumbens Extracts
|
|
Kim Kyeong-Jin
Gim Ah-Hyun
Kim Ji-Hyun
Kim Do-Hee
Lee Seo-Rin
Park Jee-Hyun
Lim Ji-Won
Ha Ji-Hoon
Park Soo-Nam
|
|
|
Abstract
|
|
|
|
In this study, the methanol fraction and aglycone fraction were made from Gynura procumbens (G. procumbens) extracts and their antioxidative effects were investigated. The free radical scavenging activity (1,1-diphenyl-2-picrylhydrazyl, DPPH), total antioxidant capacity by luminol-dependent chemiluminescence assay, and the protective effects against reactive oxygen species (ROS) in erythrocytes were measured to evaluate the antioxidative activities of the extracts. Free radical scavenging activities (FSC50) of the methanol fraction and aglycone fraction were 90.25 and 81.38 μg/mL, respectively. Total antioxidant capacities (OSC50) of the methanol fraction and aglycone fraction were 16.96 and 12.30 μg/mL, respectively. The free radical scavenging activity and total antioxidant capacity of the aglycone fraction were greater than those of methanol fraction. The cellular protective effect on the 1O2-induced cellular damage of human erythrocytes was confirmed by τ50 value. The τ50 value of the methanol fraction and agly cone fraction were 36.7 min and 76.1 min, respectively in 5 μg/mL, and the aglycone fraction showed about 2 times higher cellular protecive effect than (+)-α-tocopherol (35.4 min). These results indicate that the aglycone fraction of G. procumbens extracts has application possibility as antioxidant ingredient of cosmetic.
|
|
|
KEYWORD
|
|
|
reactive oxygen species, free radical, antioxidant, Gynura procumbens, cellular protecive effects
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|